Thalidomide 4'-oxyacetamide-PEG3-amine |
| Catalog No.GC50462 |
La talidomida 4'-oxiacetamida-PEG3-amina es un conjugado ligando-enlazador de ligasa E3 sintetizado que incorpora el ligando cereblon basado en talidomida y el enlazador PEG de 3 unidades utilizado en la tecnologÍa PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-84-9
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 1 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Functionalized Cereblon ligand for PROTACs; incorporates an E3 ligase ligand and a linker used in PROTAC technology. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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