UNC1079 |
| Catalog No.GC19367 |
UNC1079 es el anÁlogo de piperidina de UNC1021, como un inhibidor estructuralmente similar pero significativamente menos potente para usar como control negativo en estudios celulares.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1418741-86-2
Sample solution is provided at 25 µL, 10mM.
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UNC1079 is the piperidine analog of UNC1021, as a structurally similar but significantly less potent inhibitor for use as a negative control in cellular studies. Target: L3MBTL3The low anticipated affinity of UNC1079 was confirmed, as it demonstrated an activity versus L3MBTL3 of > 10 uM by AlphaScreen, which is >1000-fold weaker than UNC1215. UNC1079 also displays weak binding by ITC.
References:
[1]. James LI, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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