USP7-IN-9 |
Catalog No.GC70102 |
USP7-IN-9 is an efficient inhibitor of USP7 with an IC50 of 40.8 nM. USP7-IN-9 can induce apoptosis in RS4;11 cells and block the cell cycle at G0/G1 and S phase. USP7-IN-9 reduces the levels of cancer proteins MDM2 and DNMT1, while increasing the levels of tumor suppressor proteins p53 and p21.
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Sample solution is provided at 25 µL, 10mM.
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