VK-1727 |
| Catalog No.GC70579 |
VK-1727 es un inhibidor selectivo de una molécula pequeña de EBNA1.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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VK-1727 is a selective small molecule inhibitor of EBNA1. VK-1727 can reduce EBNA1 DNA binding activity. VK-1727 selectively blocks the proliferation and metabolic activity of EBV+ cells, instead of EBV- cells. VK-1727 is used in multiple sclerosis research.
VK-1727 (25 μM, 72 h) significantly decreases the total population of G2 cell in EBV+ cells[1].
References:
[1]. Monaco MCG, et al. EBNA1 Inhibitors Block Proliferation of Spontaneous Lymphoblastoid Cell Lines From Patients With Multiple Sclerosis and Healthy Controls. Neurol Neuroimmunol Neuroinflamm. 2023 Aug 10;10(5):e200149.
Review for VK-1727
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for VK-1727
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