VU6036720 |
| Catalog No.GC71027 |
VU6036720 es un potente y específico inhibidor in vitro de Kir4.1/5.1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3026597-12-3
Sample solution is provided at 25 µL, 10mM.
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VU6036720 can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM[1].
VU6036720 inhibits Kir4.1/5.1 activity through a reduction of channel open-state probability and single-channel current amplitude[1].
References:
[1]. Samantha J McClenahan, et al. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. Mol Pharmacol. 2022 May;101(5):357-370.
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