Zalunfiban dihydrochloride (Synonyms: RUC-4 dihydrochloride) |
| Catalog No.GC62396 |
El diclorhidrato de zalunfiban (RUC-4) es un potente antagonista selectivo de plaquetas αIIbβ3 (IC50 = 45 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI)[1].
Zalunfiban dihydrochloride (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregation performed[1].Zalunfiban dihydrochloride (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15-30 minutes that lasts from ~2 to >4.5 hours in a dose dependent manner[1].
[1]. Vootukuri S, et al. Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets. J Clin Transl Sci. 2019;3(2-3):65-74.
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