ZnAF-1F |
| Catalog No.GC67221 |
ZnAF-1F es un fluoróforo potente con un valor de Kd de 2,2 nM. ZnAF-1F se puede utilizar como sondas fluorescentes para Zn2+ en células. ZnAF-1F muestra Λ excitación de 489 nm y Λ emisión de 514 nm.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 443302-08-7
Sample solution is provided at 25 µL, 10mM.
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ZnAF-1F is a potent fluorophore for with an Kd value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn2+ in cells. ZnAF-1F shows Λ excitation of 489 nm and Λ emission of 514 nm[1][2][3].
ZnAF-1F (1 µM) shows an Kon value of 3.5*106 M-1s-1, and an Koff value of 7.7*10-3 s-1 in 100mM HEPES buffer[1].
ZnAF-1F is a Zn sensors in neutral and slightly acidic conditions[2].
[1]. Hirano T, et al. Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc. 2002 Jun 12;124(23):6555-62.
[2]. Zhaohua Dai, et al. Tailoring tripodal ligands for zinc sensing. New J. Chem., 2007,31, 1708-1718.
[3]. Que EL, et al. Metals in neurobiology: probing their chemistry and biology with molecular imaging. Chem Rev. 2008 May;108(5):1517-49.
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