ST247 |
| Catalog No.GC70423 |
ST247 a potent PPARβ/δ inverse agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1356497-91-0
Sample solution is provided at 25 µL, 10mM.
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ST247 induces a clearly enhanced interaction of the PPARβ/δ LBD with the SMRT-ID2 peptide, with an EC50 of 10 nM[1].
ST247 down-regulates basal level expression of the peroxisome proliferator responsive element-driven PPARβ/δ target gene ANGPTL4, with an IC50 of 19.1 nM[1].
References:
[1]. Naruhn S, et al. High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties. Mol Pharmacol. 2011 Nov;80(5):828-38.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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