STING-IN-4 |
| Catalog No.GC71186 |
STING-IN-4 (Compound 1) is a STING inhibitor that inhibits STING expression and hence reducing activation of STING and nuclear factor-κB (NF-κB) signaling.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2250374-27-5
Sample solution is provided at 25 µL, 10mM.
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STING-IN-4 (Compound 1) (20 μM; 26 h) inhibits NO production induced by LPS in RAW264.7 cells[1].
STING-IN-4 (2.5-10 μM; 26 h) significantly inhibits the expression of iNOS in RAW264.7 cells[1].
STING-IN-4 (5 and 50 μM; 12 h) significantly reduces STING degradation at 49, 52, and 55 °C and it may have an ability to interact with STING and enhance thermal stabilization of STING[1].
STING-IN-4 (2.5-10 μM; 8 h) inhibits LPS-induced activation of STING/IRF3/NF-κB[1].
STING-IN-4 (Compound 1) (1-9 mg/kg; i.p.; daily for 3 days) protects against LPS-induced liver injuries in mice and inhibits STING/IRF3/NF-κB activation in septic mice livers[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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