Syrosingopine |
Catalog No.GC39536 |
Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin.
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Cas No.: 84-36-6
Sample solution is provided at 25 µL, 10mM.
Syrosingopine (Su 3118) is an antihypertensive agent. Syrosingopine can decrease brain dopamine levels[1][2].
[1]. Benjamin D, et al. Syrosingopine sensitizes cancer cells to killing by metformin. Sci Adv. 2016 Dec 23;2(12):e1601756. [2]. Furukawa T, et al. Selective depleting effect of syrosingopine on brain catecholamine levels with relation to morphine analgesia in the rat. Pharmacol Biochem Behav. 1976 Apr;4(4):419-25.
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