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TMDJ-035

Catalog No.GC71097

TMDJ-035 is a selective RyR2 inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

TMDJ-035 Chemical Structure

Cas No.: 2681302-83-8

Size Price Stock Qty
5 mg
$149.00
In stock
10 mg
$234.00
In stock
25 mg
$464.00
In stock
50 mg
$743.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
TMDJ-035 is a selective RyR2 inhibitor. TMDJ-035 suppresses abnormal Ca2+ waves and transients in isolated cardiomyocytes from RyR2-mutated mice. TMDJ-035is a tool for studying the mechanism and dynamics of RyR2 channel gating.

References:
[1]. Ryosuke Ishida, et al.A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment. European Journal of Medicinal Chemistry

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