Trabectedin-d3 (Synonyms: Ecteinascidin 743-d3; ET-743-d3) |
Catalog No.GC70049 |
Trabectedin D3 (Ecteinascidin 743 D3) is the deuterated form of Trabectedin. Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent anti-tumor activity. Trabectedin binds to the minor groove of DNA, blocks stress-induced protein transcription, induces DNA backbone cleavage and cancer cell apoptosis, and increases ROS generation in MCF-7 and MDA-MB-453 cells. Trabectedin can be used for research on soft tissue sarcoma and ovarian cancer.
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Sample solution is provided at 25 µL, 10mM.
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