Volagidemab |
| Catalog No.GC72379 |
Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1233956-13-2
Sample solution is provided at 25 µL, 10mM.
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Volagidemab (5 mg/kg, s.c.) suppresses type 1 diabetes phenotype in Alloxan-induced diabetic mice[2].
References:
[1]. Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099.
[2]. Wang MY, et al. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2503-8.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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