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YO-PRO-1

Catalog No.GC71737

YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells.

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YO-PRO-1 Chemical Structure

Cas No.: 152068-09-2

Size Price Stock Qty
1 mg
$507.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
YO-PRO-1 (Oxazole yellow) is a carbocyanine monomer and DNA green fluorescent dye that is not permeable to normal animal cell membranes but is permeable to the cell membranes of apoptotic and necrotic cells. YO-PRO-1 is commonly used for the detection of apoptosis and necrosis. YO-PRO-1 has a high affinity for DNA and is essentially non-fluorescent when not bound to DNA. When apoptosis occurs, the permeability of the cell membrane changes. YO-PRO-1 can enter apoptotic cells and bind to DNA and emit bright green fluorescence. Therefore, YO-PRO-1 is often used together with propidium iodide (PI) to analyze and identify apoptotic and necrotic cells.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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